Evaluating the efficacy of intranasal oxytocin on pain and function among individuals who experience chronic pain: a protocol for a multisite, placebo-controlled, blinded, sequential, within-subjects crossover trial
Introduction Current treatments for chronic pain (eg, opioids) can have adverse side effects and rarely result in resolution of pain.As such, there is a need for adjuvant analgesics that are non-addictive, have few adverse side effects and are effective for pain management across several chronic pain conditions.Oxytocin is a naturally occurring hor